Salivary Cortisol As a Biomarker in Patients with Temporomandibular Disorder
Launched by UNIVERSITY OF COIMBRA · Mar 7, 2025
Trial Information
Current as of May 09, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying whether patients with Temporomandibular Disorder (TMD) have higher levels of a hormone called cortisol in their saliva compared to people who do not have this condition. Cortisol is often linked to stress and anxiety, and since emotional factors can contribute to TMD, researchers want to see if there’s a connection. Participants will be assessed to confirm if they have TMD using a specific set of guidelines, and then they will be divided into two groups: those with TMD and those without.
To participate in the study, individuals must be patients at the dental clinic of the University of Coimbra and should be between the ages of 65 and 74. However, pregnant women, minors, and individuals who cannot make decisions on their own are not eligible. Those who choose to join the study will need to sign a consent form and will provide a saliva sample for analysis. This research aims to better understand the relationship between stress and TMD, which could lead to improved treatments in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients who attend the dental clinic of the Faculty of Medicine of University of Coimbra
- Exclusion Criteria:
- • Pregnant women, minors and non-autonomous individuals
About University Of Coimbra
The University of Coimbra, a prestigious institution in Portugal, is dedicated to advancing medical research and innovation through its clinical trial initiatives. With a strong emphasis on collaborative research and interdisciplinary approaches, the university fosters a robust environment for the development of cutting-edge therapies and interventions. Its clinical trials aim to address critical health challenges, leveraging the expertise of its distinguished faculty and state-of-the-art facilities. Committed to ethical standards and patient welfare, the University of Coimbra plays a pivotal role in translating scientific discoveries into tangible health solutions, contributing to the global body of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Coimbra, , Portugal
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported