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Search / Trial NCT06877169

Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

Launched by CEDARS-SINAI MEDICAL CENTER · Mar 10, 2025

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Trial Information

Current as of April 23, 2025

Not yet recruiting

Keywords

Combined Heart And Kidney Transplant Simultaneous Heart And Kidney Transplant Hypothermic Oxygenated Machine Perfusion Organ Preservation

ClinConnect Summary

Combined heart and kidney transplantation (H/KTx) is the treatment of choice for patients with concomitant heart failure and chronic- or end-stage kidney disease. H/KTx presents a logistical challenge, often involving multiple surgical teams and requiring extended operative time to perform both heart and kidney transplants. Additionally, during heart transplantation, recipients require anticoagulation and multiple inotropes and vasopressors to support heart function early after implantation. While necessary, these may be detrimental to the newly implanted kidney allograft, potentially contr...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Adult patients (18 years or older) undergoing combined heart and kidney transplantation at Cedars-Sinai Medical Center.
  • Exclusion Criteria:
  • • Patients who undergo simultaneous heart/kidney transplantation in a single operative event due to medical necessity will be excluded.
  • • Patients with medical records flagged as "break-the-glass" or "research opt-out" within the center's electronic health record.

Trial Officials

Justin A Steggerda, M.D.

Principal Investigator

Cedars-Sinai Medical Center

About Cedars Sinai Medical Center

Cedars-Sinai Medical Center is a renowned nonprofit academic medical center located in Los Angeles, California, recognized for its commitment to patient care, research, and education. As a leading institution in clinical trials, Cedars-Sinai harnesses innovative approaches to advance medical knowledge and improve treatment outcomes across various specialties. With a multidisciplinary team of experts, state-of-the-art facilities, and a patient-centered approach, Cedars-Sinai actively contributes to the development of novel therapies and interventions, ensuring the highest standards of clinical research while prioritizing patient safety and ethical considerations.

Locations

Los Angeles, California, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported