CaroRite™ for Skin Health and Signs of Ageing

Launched by RDC CLINICAL PTY LTD · Mar 10, 2025

Keywords

ClinConnect Summary

This clinical trial, named CaroRite™, is looking into how a type of nutrient called carotenoids, taken as a pill, can improve skin health and reduce signs of aging in healthy women aged 40 to 55 years. The study will compare the effects of the carotenoid supplement to a placebo, which is a pill that looks the same but contains no active ingredients. The researchers want to see if taking these carotenoids can make a noticeable difference in skin condition and appearance.

To participate in this trial, women must be generally healthy, have a body mass index (BMI) between 18.5 and 29.9, and not have taken any carotenoid supplements or medications for skin conditions in the last two months. They also need to agree to keep their regular skincare routine and not change their diet or exercise habits during the study. Participants will be asked to attend scheduled visits and will be closely monitored for any changes in their skin health over the trial period. It’s important to know that women who are pregnant, nursing, or have certain medical conditions will not be eligible to join.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Females 40-55 years (inclusive)
• • Generally healthy
• • BMI 18.5-29.9 kg/m2 (inclusive)
• • Able to provide informed consent
• • Agree not to change regular skincare routine
• • Agree to not participate in another clinical trial while enrolled in this trial
• • Agree to not significantly change current diet and/or exercise frequency or intensity during study period
• Exclusion Criteria:
• • Regularly taking carotenoid containing medication/supplements within the previous 2 months
• • Have a serious illness e.g. mood disorders such as clinical depression, anxiety disorder or bipolar disorder, neurological disorders such as MS, kidney disease, liver disease or heart conditions
• • Have an unstable illness e.g. diabetes and thyroid gland dysfunction
• • Current malignancy (excluding Basal Cell Carcinoma) or chemotherapy or radiotherapy treatment for malignancy within the previous 2 years
• • Received cosmetic surgery or procedures, including Botox and other injectables, microdermabrasion and laser treatments on their face within last 3 months prior to enrolment and agree not to have these treatments during the study period.
• • Medications for acne or other skin conditions including topical retinoids (Rein-A, Retrieve) oral retinoids such as Isotretinoin (Roaccutane), benzoyl peroxide, AHA's, serum, chemical peels within 1 month prior to screening.
• • Currently taking carotenoid supplements (Beta-Carotene, Lycopene, Lutein, Zeaxanthin, Astazanthin)
• • Active smokers, nicotine use or drug (prescription or illegal substances) abuse
• • Chronic past and/or current alcohol use (\>14 alcoholic drinks week)
• • Pregnant or lactating women
• • Allergic to any of the ingredients in active or placebo formula
• • Participants who are currently participating in any other clinical trial or who have participated in a clinical trial that may affect skin health during the past 1 month
• • Any condition which in the opinion of the investigator makes the participant unsuitable for inclusion