Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery

Launched by MEDICAL UNIVERSITY OF SILESIA · Mar 10, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how different doses of morphine, a common pain medication, can be safely used during spinal anesthesia for patients undergoing total hip replacement surgery. The goal is to find out which dose provides the best pain relief while minimizing risks, such as breathing difficulties, which can occur with morphine use. Since effective pain management is crucial after surgery, researchers want to ensure that the benefits of using morphine outweigh any potential side effects.

To participate in this trial, individuals must be between the ages of 65 and 74 and be scheduled for a total hip replacement. They should be in good general health, meaning they have a body mass index (BMI) between 19 and 30 and no serious medical conditions that could complicate the use of spinal anesthesia. Participants will need to provide informed consent and will be monitored closely to ensure their safety throughout the study. This trial is not yet recruiting patients, but it aims to enhance pain management strategies following hip surgery, which may ultimately improve recovery experiences for many patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Informed consent to participate in trial
• • Qualification for total hip replacement surgery
• • ASA physical status I-III
• • BMI 19-30
• • Lack of contraindications for drugs and interventions used in trial
• Exclusion Criteria:
• • Incapability to provide informed consent
• • Contraindications for spinal anesthesia
• • Preoperative chronic pain
• • Chronic use of analgesics
• • Obesity (BMI\>30)
• • Allergies and other contraindications for drugs used in trial
• • Mental or physical incapability to operate PCA syringe pump