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Search / Trial NCT06878313

Role of Elastic Power in Acute Respiratory Distress Syndrome

Launched by HOSPITAL EL CRUCE · Mar 11, 2025

Trial Information

Current as of April 26, 2025

Not yet recruiting

Keywords

Ards Vili Mechanical Ventilation

ClinConnect Summary

This clinical trial is studying how a concept called "elastic power" relates to lung conditions in patients with acute respiratory distress syndrome (ARDS). ARDS is a serious condition that makes it difficult to breathe, and while mechanical ventilation helps these patients, it can sometimes cause additional lung injury. The researchers want to see how elastic power connects to issues like lung overinflation and how it compares to other measurements that doctors use to assess lung health during treatment.

To participate in the trial, patients must be adults aged 18 or older and diagnosed with moderate to severe ARDS. Certain patients, such as those with severe lung conditions or unstable health situations, will not be eligible. This trial is currently not recruiting participants yet, but once it starts, those who qualify can expect to undergo evaluations that will help researchers understand the role of elastic power in their lung health and treatment.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria: Adult patients (≥18 years) with moderate-to-severe acute respiratory distress syndrome (ARDS), as defined by the Berlin criteria, were prospectively and consecutively included.
  • -
  • Exclusion Criteria: Patients were excluded if they met at least one of the following criteria:
  • History of emphysema, asthma, or pneumothorax.
  • Severe instability at the time of the study preventing the PEEP titration maneuver, defined by at least one of the following indicators: SaO₂ ≤ 90%, shock requiring \>0.5 γ/kg/min of norepinephrine, complex arrhythmia, myocardial ischemia, or intracranial hypertension refractory to initial treatment.
  • Patients with do-not-resuscitate orders and pregnant women.

About Hospital El Cruce

Hospital El Cruce is a leading healthcare institution dedicated to advancing medical research and improving patient outcomes through innovative clinical trials. Located in Buenos Aires, Argentina, the hospital is renowned for its multidisciplinary approach, combining cutting-edge technology with a commitment to evidence-based practices. As a clinical trial sponsor, Hospital El Cruce prioritizes patient safety and ethical standards while fostering collaboration with researchers and healthcare professionals. The institution aims to contribute valuable insights to the medical community by exploring new therapies and treatment modalities across various fields, ultimately enhancing the quality of care for diverse patient populations.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported