Plate vs. Screw for Guided Growth in Coronal Knee Deformities

Launched by ASSIUT UNIVERSITY · Mar 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two different surgical techniques to help correct knee deformities in children. The techniques being compared are called Tension Band Plate (TBP) and Percutaneous Epiphysiodesis by Transphyseal Screw (PETS). The main goal of the study is to find out which method works better for fixing these knee problems and whether one technique causes fewer complications or has a quicker recovery time than the other.

To be part of this study, children and adolescents aged 4 to 16 who have certain types of knee deformities may be eligible if they still have growth remaining in their bones. Participants will have one of the two surgeries to correct their knee deformity and will need to attend follow-up visits so the doctors can check how well the surgery worked through X-rays and other evaluations. It's important to note that some children with specific health issues affecting bone growth may not qualify for this trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Children and adolescents beyond the age of physiological varus/valgus correction (i.e., typically ≥4 years for genu varum and ≥7 years for genu valgum) with Mechanical Axis Deviation (MAD) in lower limbs and abnormal joint orientation angles, in the coronal plane either femoral or tibial.
• • 2. Open physis (growth plate) on radiographs and at least one year of growth remaining before age of skeletal maturity (typically ≤14 years in females, ≤16 years in males).
• Exclusion Criteria:
• • 1. Sick Physis as in Blount's disease stages III-V or any partial or total physeal arrest caused by trauma, inflammation or neoplasia.
• 2. Uncorrectable systemic disorders affecting bone growth and alignment, including but not limited to:
• • i- Severe metabolic disorders (e.g., advanced rickets, hypophosphatasia, mucopolysaccharidoses) ii- Uncontrolled endocrine disorders (e.g., untreated hypothyroidism, growth hormone abnormalities) iii- Severe connective tissue disorders (e.g., osteogenesis imperfecta, advanced Ehlers-Danlos syndrome) iv- Chronic inflammatory or hematologic conditions that impair bone growth (e.g., severe juvenile idiopathic arthritis, advanced sickle cell disease)