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Search / Trial NCT06879171

Radiographic and Histomorphometric Assessment for Alveolar Ridge Preservation Using Autogenous Tooth Graft From Extracted Tooth Combined With Simvastatin 1:1 Versus Autogenous Tooth Graft

Launched by CAIRO UNIVERSITY · Mar 11, 2025

Trial Information

Current as of April 22, 2025

Not yet recruiting

Keywords

Autogenous Tooth Graft Simvastatin Delayed Implant Alveolar Ridge Preservation

ClinConnect Summary

Alveolar ridge resorption following tooth extraction is one of the greatest challenges in dentistry, especially for patients seeking dental implants. The alveolar ridge undergoes significant decrease in bone dimensions which will complicate the implant placement and thus necessitate additional grafting procedures to compensate the bone loss. Bone height decreases progressively by 25% during the first year after tooth loss, with a total of 4 mm of height lost during this first year post-extraction.

So various grafting materials such as Autogenous bone grafts, bone substitutes and allografts...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with badly broken, non-restorable, or periodontally hopeless non molar single rooted teeth.
  • Age from 20-45 years old(6,13). No sex predilection.
  • Medically free from any medical condition that would interfere with bone healing.
  • Patients with status classification (ASA I \& II) with adequate oral hygiene condition.
  • Alveolar sockets free from any preexisting periapical pathology based on intraoral periapical or panoramic radiograph.
  • Exclusion Criteria:
  • Patients with any medical condition that contraindicated the procedure and general contraindications for Implant Surgery(6,13)
  • Patients who are allergic to Simvastatin drug.(6)
  • Presence of active infection around the tooth or remaining root.
  • Psychological reasons that might affect the procedure or the subsequent follow up visits.
  • Heavy smokers
  • Immunosuppressed or Immunocompromised.(13)

Trial Officials

Nadia Galal professor, phd holder

Principal Investigator

Cairo University

About Cairo University

Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported