Radiographic and Histomorphometric Assessment for Alveolar Ridge Preservation Using Autogenous Tooth Graft From Extracted Tooth Combined With Simvastatin 1:1 Versus Autogenous Tooth Graft

Launched by CAIRO UNIVERSITY · Mar 11, 2025

Keywords

ClinConnect Summary

Alveolar ridge resorption following tooth extraction is one of the greatest challenges in dentistry, especially for patients seeking dental implants. The alveolar ridge undergoes significant decrease in bone dimensions which will complicate the implant placement and thus necessitate additional grafting procedures to compensate the bone loss. Bone height decreases progressively by 25% during the first year after tooth loss, with a total of 4 mm of height lost during this first year post-extraction.

So various grafting materials such as Autogenous bone grafts, bone substitutes and allografts...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with badly broken, non-restorable, or periodontally hopeless non molar single rooted teeth.
• • Age from 20-45 years old(6,13). No sex predilection.
• • Medically free from any medical condition that would interfere with bone healing.
• • Patients with status classification (ASA I \& II) with adequate oral hygiene condition.
• • Alveolar sockets free from any preexisting periapical pathology based on intraoral periapical or panoramic radiograph.
• Exclusion Criteria:
• • Patients with any medical condition that contraindicated the procedure and general contraindications for Implant Surgery(6,13)
• • Patients who are allergic to Simvastatin drug.(6)
• • Presence of active infection around the tooth or remaining root.
• • Psychological reasons that might affect the procedure or the subsequent follow up visits.
• • Heavy smokers
• • Immunosuppressed or Immunocompromised.(13)

Trial Officials