Genetic Variants of Annexin A2 and Cryptogenic Stroke

Launched by CENTRE HOSPITALIER UNIVERSITAIRE, AMIENS · Mar 11, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how certain genetic changes in a gene called ANXA2 might be linked to ischemic strokes, which are strokes caused by blocked blood flow to the brain. Strokes can happen for many reasons, but sometimes, especially in younger people, doctors can't find out what caused it. Previous research suggests that ANXA2 plays an important role in breaking down blood clots, and this study aims to see if specific variations in the ANXA2 gene can increase the risk of having a stroke.

To participate in this trial, individuals must be at least 18 years old and have experienced a completed ischemic stroke, meaning they had a sudden loss of brain function that lasted more than 24 hours. People who have had a transient ischemic attack (a temporary stroke-like episode) or are pregnant cannot take part. The trial is not yet recruiting, but once it starts, participants will have a chance to contribute to important research that could help us understand more about the causes of stroke and how to prevent it.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Completed ischemic stroke defined as a rapidly developing focal neurologic deficit with no apparent cause other than a vascular origin that persisted beyond 24 hours in surviving patients
• • Age from 18 years old
• Exclusion Criteria:
• • Transient ischemic attack
• • Pregnancy