Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study

Launched by NORTHWESTERN UNIVERSITY · Mar 11, 2025

Keywords

ClinConnect Summary

The iCARE trial is studying two different approaches to help young people in Nigeria who are affected by HIV. The goal is to find out how effective these methods are in both identifying individuals who may have HIV and providing treatment. The trial will involve young people aged 15 to 24 and will run for 48 weeks. Participants will receive support through mobile health tools and peer navigators to help them understand and manage their health better.

To be eligible for the trial, you need to be between 15 and 24 years old. If you are interested in the HIV Case Finding Intervention, you must be HIV-negative and comfortable speaking basic English or one of the local languages. For the HIV Treatment Intervention, you must be HIV-positive and starting treatment for the first time. Throughout the study, you will receive guidance and assistance, and your participation will help improve HIV care for other young people in Nigeria. If you are under 18, you'll need permission from a parent or guardian to join.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• HIV Case Finding Intervention:
• • Aged 15 to 24
• • Male birth sex of any current gender identity
• • Understand basic English, Yoruba, Hausa, Igbo or Pidgin English For the PrEP component, must also be HIV-negative
• HIV Treatment Intervention:
• • Aged 15 to 24
• • HIV seropositive
• • Initiating ART for the first time at a Clinical Research Performance Site (CRPS) clinic or satellite clinic
• • Understand basic English, Yoruba, Hausa, Igbo or Pidgin English
• • Intention to remain a CRPS patient during follow-up
• Exclusion Criteria:
• • Unable to provide consent
• • No parental permission if aged 15 and not emancipated