Minimally Invasive Surgical Intervention for Hirschsprung Disease
Launched by NATIONAL CHILDREN'S HOSPITAL, VIETNAM · Mar 13, 2025
Trial Information
Current as of April 30, 2025
Completed
Keywords
ClinConnect Summary
Hirschsprung's disease (HD) is one of the most common congenital disorders affecting the gastrointestinal tract, with a global incidence of approximately 1 in 5,000 live births. However, studies suggest that the prevalence is notably higher in the Vietnamese population. The condition arises due to the absence of enteric ganglion cells in the distal colon, leading to a functional obstruction that prevents normal bowel motility. This defect results in delayed meconium passage in newborns, severe constipation, abdominal distension, and feeding intolerance. If left untreated, HD can progress to...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • All patients diagnosed with Hirschsprung's Disease, admitted to the National Children's Hospital between January 2017 and December 2023, exhibiting clinical signs and symptoms consistent with Hirschsprung's disease.
- • Minimally invasive laparoscopic pull-through surgery was performed
- Exclusion Criteria:
- • Patients demonstrating clinical instability characterized by signs of peritonitis or intestinal perforation necessitating conventional laparotomy.
- • Patients whose biopsy results are not consistent with Hirschsprung's disease
About National Children's Hospital, Vietnam
National Children's Hospital, Vietnam, is a leading pediatric healthcare institution committed to advancing child health through innovative research and clinical trials. With a focus on improving treatment outcomes and enhancing healthcare delivery for children, the hospital collaborates with international and local partners to conduct rigorous clinical studies across various pediatric specialties. Its multidisciplinary team of healthcare professionals and researchers is dedicated to fostering a safe and ethical environment for clinical research, ensuring the highest standards of care and scientific integrity in all trials. Through its initiatives, National Children's Hospital aims to contribute significantly to the global body of pediatric knowledge and improve health outcomes for children in Vietnam and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hanoi, , Vietnam
Patients applied
Trial Officials
Quang T Nguyen, M.D.
Principal Investigator
Department of Pediatric Surgery, The National Hospital of Pediatrics, Hanoi, Vietnam
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported