Minimally Invasive Surgical Intervention for Hirschsprung Disease

Launched by NATIONAL CHILDREN'S HOSPITAL, VIETNAM · Mar 13, 2025

Keywords

ClinConnect Summary

Hirschsprung's disease (HD) is one of the most common congenital disorders affecting the gastrointestinal tract, with a global incidence of approximately 1 in 5,000 live births. However, studies suggest that the prevalence is notably higher in the Vietnamese population. The condition arises due to the absence of enteric ganglion cells in the distal colon, leading to a functional obstruction that prevents normal bowel motility. This defect results in delayed meconium passage in newborns, severe constipation, abdominal distension, and feeding intolerance. If left untreated, HD can progress to...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age: From 1 to 28 days old
• • Diagnosis: Hirschsprung disease was diagnosed based on clinical presentation, intraoperative frozen section biopsy, and postoperative histopathological findings showing absence of ganglion cells.
• • Surgical Approach: Patients underwent SILEP through a single periumbilical incision, with no additional abdominal incisions. All surgeries were conducted by the same team, and postoperative care was provided according to a standardized protocol.
• • Parents or guardians provided consent to participate in the study and committed to following the scheduled follow-up visits.
• Exclusion Criteria:
• • Patients exhibiting severe HAEC, bowel obstruction, or peritonitis at the time of operation
• • Those with a history of failed Hirschsprung disease surgery, prior abdominal operations, or colostomy
• • Individuals with contraindications to laparoscopic procedures, such as bleeding disorders or significant congenital heart defects
• • Cases where parents or legal guardians refused consent for study participation