Ultrasound Acute Chest Syndrome Sickle Cell Disease

Launched by INDIANA UNIVERSITY · Mar 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at the use of ultrasound to help diagnose a serious complication called Acute Chest Syndrome in children and young adults with sickle cell disease. The goal is to see how reliable and useful ultrasound can be in a hospital setting for patients who are dealing with issues related to their sickle cell disease. The trial is currently recruiting participants, specifically those aged 0 to 25 years who have been hospitalized for complications related to their condition.

To be eligible for this study, participants must have a confirmed diagnosis of sickle cell disease and be admitted to the hospital for treatment. However, patients who are unstable or who have already been diagnosed with Acute Chest Syndrome before their hospital stay will not be included. If you or a loved one is eligible and chooses to participate, you can expect to undergo ultrasound examinations as part of the study, which will help researchers understand how effective this method is in managing complications of sickle cell disease.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age: 0-25 years old
• • 2. Diagnosis: Patients with a documented diagnosis of sickle cell disease (any genotype)
• • 3. Disposition: Hospitalized for a SCD-related complication (e.g. VOC)
• Exclusion Criteria:
• • 1. Patient is considered hemodynamically unstable to undergo consent and study procedures
• • 2. Already has diagnosis of ACS prior to admission to inpatient unit
• • 3. POCUS operator not available