Mini-Crush or Controlled Balloon-Crush for True Coronary Bifurcation Lesions

Launched by ISTANBUL MEHMET AKIF ERSOY EDUCATIONAL AND TRAINING HOSPITAL · Mar 17, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two techniques, known as mini-crush and controlled balloon-crush, for treating complex heart conditions called coronary bifurcation lesions. These lesions occur where a coronary artery branches into two smaller arteries, and the goal is to improve blood flow to the heart while minimizing complications like heart attacks or strokes. The trial compares how well these two methods work in patients with specific types of bifurcation lesions, focusing on how safely and effectively they can be performed.

To be eligible for this trial, participants must be over 18 years old and have a complex coronary bifurcation lesion. Some individuals may not qualify if they have certain conditions, such as simpler bifurcation anatomy or serious health issues like advanced liver or kidney disease. Those who join the study can expect to undergo a procedure using one of the stenting techniques and will be monitored for one year to see how well they recover and if there are any complications. It's important to know that this research aims to improve treatment options for patients with these challenging heart conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged \>18
• • PCI with mini-crush or controlled balloon-crush
• • Complex coronary bifurcation lesion (Medina 0.1.1 and Medina 1.1.1)
• Exclusion Criteria:
• • Non-complex bifurcation anatomy
• • Bail-out 2-stent (reverse mini-crush or reverse controlled balloon-crush)
• • ST-elevation myocardial infarction
• • Cardiogenic shock status
• • In-stent restenosis
• • A history of coronary artery bypass grafting
• • Implantation of bare-metal stent
• • End-stage hepatic or renal disease
• • \<1-year life expectancy