ClinConnect ClinConnect Logo
Search / Trial NCT06883396

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

Launched by HOSPITAL FOR SPECIAL SURGERY, NEW YORK · Mar 12, 2025

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

Patella Patella Dislocation Patellar Instability Recurrent Patellar Instability Mpfl Medial Patellofemoral Ligament Medial Patellofemoral Ligament Reconstruction Patellofemoral Instability

ClinConnect Summary

The JUPITER 4.0 trial is studying the outcomes of a surgery called medial patellofemoral ligament (MPFL) reconstruction, which is used to treat people who frequently experience knee cap dislocations, a condition known as recurrent patellar instability. Researchers want to find out what factors might lead to further knee problems after this surgery and how well patients feel their knees are functioning one and two years after the operation.

To participate in this study, individuals need to be between 10 and 35 years old and have a history of patellar instability, meaning they have had at least one dislocated kneecap that required medical attention or meets certain other criteria. During the study, participants will fill out surveys about their knee health and activity levels at one and two years post-surgery. This research aims to help doctors better understand how to improve outcomes for patients with knee instability.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 10-35 years old
  • Recurrent patellar instability with at least one episode defined as either (1) a dislocated patella requiring reduction in the emergency department or (2) a convincing history for dislocation, associated with full giving way, and the following physical findings: (a) hemarthrosis or effusion, (b) tenderness along the medial retinaculum, and (c) apprehension when laterally directed force was applied to the patella or (3) MRI-documented dislocation with associated bone bruises
  • Exclusion Criteria:
  • Previous ipsilateral knee surgery
  • Obligatory/fixed/habitual patella dislocation or subluxation
  • Unloadable inferior or lateral chondral damage on the patella that would require a tibial tubercle transfer for unloading purposes
  • Pathologic tibiofemoral instability

About Hospital For Special Surgery, New York

The Hospital for Special Surgery (HSS) in New York is a world-renowned institution specializing in orthopedic surgery, rheumatology, and rehabilitation. Recognized for its commitment to advancing medical research and improving patient outcomes, HSS serves as a leading clinical trial sponsor, facilitating innovative studies that explore cutting-edge treatments and therapies. With a team of expert clinicians and researchers, HSS aims to enhance clinical practices through rigorous scientific inquiry, ultimately contributing to the advancement of musculoskeletal health and patient care on a global scale.

Locations

Rochester, Minnesota, United States

Boston, Massachusetts, United States

New York, New York, United States

Iowa City, Iowa, United States

Cincinnati, Ohio, United States

Cleveland, Ohio, United States

Portland, Oregon, United States

Boston, Massachusetts, United States

Chicago, Illinois, United States

Gainesville, Florida, United States

Redwood City, California, United States

New York, New York, United States

Dallas, Texas, United States

New York, New York, United States

Wake Forest, North Carolina, United States

Dublin, Ohio, United States

Patients applied

0 patients applied

Trial Officials

Beth Shubin Stein, MD

Principal Investigator

Hospital for Special Surgery, New York

Shital Parikh, MD

Principal Investigator

Children's Hospital Medical Center, Cincinnati

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported