Diagnostic Accuracy of the Optic Nerve Deformability Index and Optic Nerve Sheath Diameter as a Noninvasive Predictor of Intracranial Pressure

Launched by BENHA UNIVERSITY · Mar 13, 2025

Keywords

ClinConnect Summary

Operational Design:

Preparation:

Awake and alert patients should be briefed on the procedure. Obtunded, intubated, or heavily sedated patients should undergo a basic eye evaluation for signs and symptoms of globe rupture or hyphema. If there is evidence of globe rupture-including visible conjunctival or scleral defects, severe chemosis, 360-degree conjunctival hemorrhage, hypotony, or total hyphema-the procedure should be aborted to avoid further herniation of intraocular contents, and an ophthalmologist should be consulted. The patient's position should be determined by comfort and ease ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age 18 to 65 years
• • increased ICP (e.g., TBI, sub arachnoid hemorrhage, intracranial hemorrhage)
• • a Glasgow Coma scale=3-12 and requiring ICP monitoring via invasive methods (e.g. extra ventricular drain, lumber drain)
• Exclusion Criteria:
• • chronic hydrocephalus
• • extensive local orbit trauma
• • a pre-existing ocular disease affecting the optic nerve and/or orbital cavity
• • hyperthyroidism with exophthalmia
• • facial trauma affecting the orbits and/or eyeballs
• • optic nerve trauma
• • signs of critically raised ICP, needing urgent surgery.
• • hemodynamically unstable between ONSD acquisition and ICP measurement.
• • receiving medication that would decrease ICP between ultrasound imaging and ICP measurement, i.e. mannitol, hypertonic saline or steroids.

Trial Officials