The Effect of Cytisine Treatment for Smoking Cessation on Cardiovascular Function in Adult Smokers
Launched by UNIVERSITY OF ATHENS · Mar 13, 2025
Trial Information
Current as of May 10, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of a treatment called cytisine to help adult smokers quit smoking and to see how it affects heart health. Cytisine is a plant-based medication that can help people who are dependent on nicotine, the addictive substance in cigarettes. The main goal of the study is to find out if cytisine is effective for quitting smoking over a 25-day period and how it impacts heart function, including the stiffness of blood vessels and overall heart health.
To participate, you need to be a smoker who is interested in quitting. The study is looking for at least 200 participants, and some will receive cytisine, while others might get nicotine replacement therapy or no treatment at all as a control group. Throughout the study, participants will receive support and counseling, and their heart health will be monitored through various tests at the start, one month later, and again after six months. This research aims to provide important information about how cytisine can help people quit smoking and its effects on cardiovascular health, which is vital for overall well-being.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Smokers willing to participate
- Exclusion Criteria:
- • history of coronary artery disease, active malignancy, history of severe liver and renal failure, history of autoimmune disease.
About University Of Athens
The University of Athens, a leading institution in medical research and education, is dedicated to advancing healthcare through innovative clinical trials. With a robust infrastructure and a multidisciplinary team of experts, the university focuses on translating scientific discoveries into practical applications that benefit patient care. Its commitment to ethical standards and rigorous methodologies ensures that all trials conducted under its auspices adhere to the highest principles of research integrity. By fostering collaboration with national and international partners, the University of Athens aims to contribute significantly to the global medical community and improve health outcomes through evidence-based practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Athens, Haidari, Greece
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported