Effectiveness of Curcuminoids in Controlling Postoperative Pain Following Total Laparoscopic Hysterectomy

Launched by ERZINCAN MILITARY HOSPITAL · Mar 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how effective curcuminoids, the active ingredient in turmeric, are at managing pain after a total laparoscopic hysterectomy (TLH), which is a common surgery for women. Even though TLH offers benefits like quicker recovery and less visible scars, many patients still experience significant pain after the procedure. The trial aims to see if using curcuminoids can help reduce this postoperative pain and improve overall recovery.

Women who are eligible for this study will be those scheduled to undergo laparoscopic total hysterectomy and possibly some additional procedures. To participate, they need to be able to understand and sign a consent form and keep a pain diary. However, certain individuals, such as those with chronic pain conditions or those who frequently use pain medications, won't be included. The trial is not yet recruiting participants, but once it begins, women who join can expect to receive information about their pain levels and quality of life during their recovery. This study is important because it explores a low-cost and traditional approach to improving pain management after surgery.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • -Laparoscopic total hysterectomy and salpingectomy, with the option of additional procedures such as oophorectomy, uterosacral ligament plications, trans obturator tape insertion, or sentinel lymphadenectomy candidates
• • They should be able to understand and sign an informed consent
• • They should be literate enough to understand the maintenance of a diary recording pain scores, QoL-15 scores, and any adverse event
• Exclusion Criteria:
• • Patients with any peripheral or central neuropathic pain
• • Patients used to taking over-the-counter painkiller pills
• • Patients with a history of alcohol intake/drug dependence
• • Patients with a history of psychosis
• • \*Patients with chronic inflammatory diseases who cannot be taken off nonsteroidal anti-inflammatory drugs (NSAIDs)/painkillers
• • Patients on immunosuppressive/cytotoxic/steroid therapy. \*Patients with a known allergy to duloxetine