Effect of Continuous Intake of Ergothioneine-containing Supplements on Skin Condition

Launched by SHANGHAI EGT SYNBIO GROUP CO., LTD. · Mar 13, 2025

Keywords

ClinConnect Summary

Ergothioneine (EGT), a naturally occurring amino acid-like antioxidant, was first discovered in Clavieps purpurea in 1909. It is widely found in mushrooms, legumes, and certain animal tissues. Studies have shown that ergothioneine protects skin cells by scavenging free radicals and reducing oxidative stress, thereby delaying skin aging. Additionally, it can inhibit melanin production, improve uneven skin tone, enhance the skin barrier function, and boost skin elasticity and radiance. In recent years, with growing attention to nutricosmetics, ergothioneine has gained significant interest for...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • ① Healthy women aged 35 to 59 years old.
• • ② Individuals who feel that their skin condition is deteriorating (loss of radiance, dullness, pigmentation spots, etc.).
• Exclusion Criteria:
• • Individuals with a history of food allergies.
• • Pregnant or breastfeeding individuals.
• • Individuals with inflammation or wounds on their face.
• • Individuals taking medication that could affect the trial. ⑤ Individuals consuming health supplements that could affect the trial.
• • ⑥ Individuals currently undergoing medical treatment or receiving prescriptions from a doctor.
• • ⑦ Individuals undergoing hormone therapy.
• • ⑧ Individuals with eyelash extensions, permanent eyeliner, or other forms of cosmetic tattooing around the eyes.
• • ⑨ Individuals who have participated in human clinical trials within the last month or plan to do so during the trial period.
• • ⑩ Individuals deemed unsuitable by the principal investigator of the trial.