Deep Sedation With Pre-emptive Endotracheal Intubation for Advanced Bronchoscopy Procedures

Launched by PUSAN NATIONAL UNIVERSITY YANGSAN HOSPITAL · Mar 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a technique called deep sedation with a method known as pre-emptive intubation, which is used during bronchoscopy procedures. Bronchoscopy is a medical procedure that helps doctors diagnose and treat lung diseases. The goal of the trial is to see if using deep sedation along with intubation before the procedure can make it safer and more effective, especially for patients who need complex treatments. This study will take place across multiple hospitals and aims to gather information about how well this method works and any potential risks involved.

To participate in this trial, patients need to require a bronchoscopy for diagnosis or treatment and must agree to join the study by signing a consent form. However, certain patients are not eligible, such as those who have had a recent heart attack or stroke, those with serious health conditions, or anyone who is pregnant. Participants can expect to be closely monitored throughout the procedure to ensure their safety and comfort. This trial is still in the planning stages and has not started recruiting participants yet.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients requiring a bronchoscopy-assisted procedure for diagnostic or therapeutic purposes
• • Individuals who voluntarily consent to participate in the clinical study and sign a written informed consent form
• Exclusion Criteria:
• • Patients who have experienced acute myocardial infarction or acute stroke within the past six weeks
• • Patients with contraindications to bronchoscopy (e.g., severe respiratory or cardiovascular comorbidities)
• • Patients with a history of allergy to benzodiazepines, propofol, fentanyl, or flumazenil
• • Patients with genetic disorders such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
• • Patients with a severe hypersensitivity reaction to dextran 40
• • Patients with a history of acute angle-closure glaucoma
• • Pregnant women
• • Prisoners
• • Patients with psychiatric disorders
• • Patients classified as ASA Physical Status IV or V by the American Society of Anesthesiologists (ASA)
• • Any other patients deemed unsuitable for the clinical study by the investigator