The Effect of Dual-tasking Program on Cognitive and Physical Functions and Independence in Activities of Daily Living in Children With Duchenne Muscular Dystrophy: A Single-blind Randomized Controlled Trial
Launched by LOKMAN HEKIM ÜNIVERSITESI · Mar 13, 2025
Trial Information
Current as of September 05, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Duchenne Muscular Dystrophy (DMD) is an X-linked recessive disorder characterized by progressive muscle degeneration, as well as frequent developmental, cognitive, and behavioral impairments, with a prevalence of one in 5,000 live male births. It is caused by mutations in the dystrophin gene, leading to the absence or severe deficiency of dystrophin, a cytoskeletal protein essential for the strength, stability, and functionality of myofibrils. Although boys with DMD appear normal at birth, difficulties in developmental milestones such as independent walking and standing become apparent duri...
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • Being a boy between the ages of 6-12 years who has been diagnosed with DMD as a result of specialist evaluation and gene analysis,
- • Being in stage 1 and stage 2 according to Vignos lower extremity classification,
- • A score of 27 and above on the Modified Mini-Mental Test,
- • To have the ability to walk at least 10 meters independently,
- • Receiving at least 8 physiotherapy and rehabilitation sessions for 1 month,
- • Volunteering to participate in the study by their parents and reading and signing the informed consent form.
- Exclusion Criteria:
- • Having a neurological disease other than DMD and/or another diagnosed neurological disease accompanying DMD,
- • To have had any injury and/or surgery within the last six months,
- • Having a co-operation problem that prevents completing the assessments for any reason,
- • Having difficulty understanding and speaking the Turkish language.
About Lokman Hekim üniversitesi
Lokman Hekim Üniversitesi is a distinguished academic institution dedicated to advancing healthcare through innovative research and clinical trials. Committed to fostering a collaborative environment, the university integrates cutting-edge scientific inquiry with practical applications to enhance patient care and outcomes. With a focus on interdisciplinary approaches, Lokman Hekim Üniversitesi actively engages in partnerships with healthcare professionals and industry leaders to drive forward-thinking solutions in medical science. Their clinical trials aim to contribute valuable insights to the global medical community, ensuring the highest standards of ethical conduct and rigor in research practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ankara, Cankaya, Turkey
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported