Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years Old

Launched by AL-MUSTANSIRIYAH UNIVERSITY · Mar 15, 2025

Keywords

ClinConnect Summary

100 subjects will be enrolled, who show generalized gingivitis (moderate gingivitis) with no Periodontal pocket depth\>3 mm, intact periodontium, and no loss of periodontal attachment), caused by the accumulation of plaque. 50 subjects are case that given a lozenge containing propolis and oral hygiene instructions, and 50 subjects were control that were given oral hygiene instructions only. The participants will be asked to chew a lozenge twice per day and Discontinuation of the lozenges will be advised in cases of any allergic reaction. in baseline visit at the beginning, Saliva collection...

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Age of patients (19_24) who volunteered to participate.
• • 2. Apparently, good general health. With no systemic diseases.
• • 3. plaque and gingival indices were ranged from (1.1_2.0)
• Exclusion Criteria:
• • 1. Individuals with chronic illnesses, immunocompromised individuals, pregnant women, those on contraceptive medications, and breastfeeding mothers.
• • 2. People who use mouthwash at the moment or any preventive modalities. 3. Those taking anti-inflammatory drugs and antibiotics both during the study and in the final four weeks prior.
• • 4. Individuals have a history of hypersensitivity to any substance utilized in the current investigation.
• • 5. Individuals who have undergone a recent tooth extraction. 6. Individuals with Periodontal pocket depth Equal or less than 4 or attachment loss.
• • 7. Individuals who smoke. 8. Individuals with orthodontic equipment, removable dentures, implants.