Comparative Study Between Oxytocin Infusion Before and After Placental Delivery on Blood Loss During and After Cesarean Delivery .
Launched by CAIRO UNIVERSITY · Mar 17, 2025
Trial Information
Current as of May 09, 2025
Completed
Keywords
ClinConnect Summary
Participants were randomized using computer-generated random numbers into 2 groups. Group I included 32 women who received oxytocin infusion before placental delivery just after cord clamping and group II included 32 women who received oxytocin infusion after placental delivery. In both groups 10 IU of oxytocin (Syntocinon, Novartis, Basel, Switzerland) were diluted in 500 mL of normal saline and administered through intravenous infusion over 30 minutes.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Age 18 - 40 years
- • singleton full term pregnancy.
- • Candidate for elective cesarean delivery under spinal anaesthesia
- Exclusion Criteria:
- • women at high risk for intraoperative bleeding as those with placenta previa or other placental abnormalities
- • women with bleeding or coagulation disorders.
- • Medical disorder associating pregnancy as preeclampsia or diabetes
- • Allergy or contraindications to oxytocin
- • Fetal macrosomia, or congenital anomalies
- • Polyhydramnios
- • Uterine abnormalities as fibroids
- • Women with intraoperative complications as vascular or visceral injuries
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Trial Officials
Ahmed Maged, MD
Principal Investigator
Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported