Supplement Combination on Stress and Sleep

Launched by UNIVERSITY OF SOUTH CAROLINA · Mar 16, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how a combination of supplements can affect sleep quality and stress levels in healthy adults. If you're between the ages of 18 and 50, have a healthy body weight, and are physically active (like exercising regularly), you might be eligible to participate. Participants should also be able to read and understand study materials and have an Apple device with the latest software to use during the trial.

If you join the study, you'll be asked to follow some guidelines about any supplements you might currently be taking. You won't be able to participate if you have certain health issues, like allergies to the supplements being tested or conditions that affect sleep or stress. Throughout the trial, you'll share information about your sleep and stress levels, and your experience will help researchers understand how these supplements work. Remember, your safety is a top priority in this study!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy participants aged 18 to 50 years (inclusive) at the time of screening with a body mass index of 18.5 to 29.9 kg/m2.
• • Willing to give voluntary consent, be able to understand and read the questionnaires, carry out all study-related procedures, communicate effectively with the study staff, and agree to allow any study-related evaluations.
• • Participant is physically active: participating in resistance and/or endurance exercise ≥150 min/wk for ≥6 mo.
• • Participant will be asked about dietary supplementation use within the past 6 months.
• • If participant began taking a supplement within the past month, participant will be asked to discontinue supplement use followed by a 2-week washout prior to participation.In all other cases, supplement use will be asked to be maintained throughout the study.
• • • The participant has an apple device with iOS 16 or greater software.
• Exclusion Criteria:
• • Have a known sensitivity of allergy to any of the investigational products.
• • Participants currently taking any of the investigational products will be excluded.
• • Female participants who are lactating, pregnant, or planning to become pregnant during the study.
• • Diagnosed with any sleep-related or stress-related disorders.
• • Currently taking medication to manage sleep or cortisol levels.
• • Participants with controlled or uncontrolled hypertension including stage 1 hypertension (systolic blood pressure ≥129 mmHg and diastolic blood pressure ≥89 mmHg).
• • Any other condition or abnormality that, in the opinion of the investigator, would compromise the safety of the participant or the quality of the study data.