The Effect of Low-Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Stroke Patients

Launched by ANKARA CITY HOSPITAL BILKENT · Mar 17, 2025

Keywords

ClinConnect Summary

Post-stroke spasticity is a common complication that can severely impact daily living activities, causing pain and hygiene challenges for a significant number of patients. Spasticity is a clinical condition that arises as a result of abnormal or hyperexcitable spinal reflexes, and the excitability of the spinal stretch reflex is regulated through supraspinal descending pathways such as the Dorsal Reticulospinal tract, Medial Reticulospinal tract, and Vestibulospinal tract. The treatment of spasticity can be categorized into non-pharmacological, pharmacological, and surgical approaches. Phar...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Having a lesion in a single hemisphere confirmed by MRI,
• • At least 6 months and at most 2 years having passed since the stroke,
• • Spasticity in wrist flexors and finger flexors at levels 1+, 2, or 3 according to the modified Ashworth scale,
• • Being between 18-75 years old,
• • Having a Mini-Mental Test score of ≥ 24,
• • If using antispastic medication, no change in medication dosage in the last month.
• Exclusion Criteria:
• • History of epilepsy, dementia, cognitive impairment, or neurodegenerative disease,
• • Having a metallic materials in the area to be stimulated (such as a cochlear implant, brain pacemaker, or drug pump),
• • Alcoholism,
• • Pregnancy,
• • Severe and newly decompensated heart failure,
• • Using medications that lower the seizure threshold.

Trial Officials