Hysteroscopy for Chronic Endometritis: Diagnostic Performance and Observer Variability
Launched by TUNIS UNIVERSITY · Mar 17, 2025
Trial Information
Current as of May 09, 2025
Completed
Keywords
ClinConnect Summary
This study evaluates the diagnostic performance of hysteroscopy in detecting chronic endometritis (CE), a condition associated with female infertility. CE is characterized by persistent endometrial inflammation and is challenging to diagnose due to its nonspecific clinical presentation. Histopathological examination with CD138 immunohistochemistry (IHC) is currently the gold standard for CE diagnosis, yet hysteroscopy remains a commonly used tool in clinical practice.
This prospective, multicenter study was conducted between June 6, 2021, and August 8, 2022, and included infertile women ag...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • included women aged 18 to 42 years, consulting for infertility, with a pelvic ultrasound showing no uterine abnormalities
- Exclusion Criteria:
- • Excluded from the study were patients with biological inflammatory syndrome, those on antibiotic therapy or with a recent acute genital infection (less than three months), autolysed biopsies, unusable hysteroscopy videos, atypical hyperplasia, or endometrial cancer.
About Tunis University
Tunis University is a leading academic institution in Tunisia, dedicated to advancing research and education in various fields, including medicine and health sciences. As a clinical trial sponsor, Tunis University leverages its robust network of researchers, state-of-the-art facilities, and commitment to ethical standards to conduct innovative clinical studies aimed at improving patient outcomes. The university collaborates with local and international partners to facilitate cutting-edge research, fostering an environment of academic excellence and contributing to the global body of medical knowledge. Through its clinical trials, Tunis University aims to address pressing health challenges and enhance the quality of care in the region and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Manouba, Tunis, Tunisia
Patients applied
Trial Officials
Haithem Aloui
Principal Investigator
Tunis University Manar
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported