Videodensitometric Angiographic Assessment of AR in the Cath-lab for Intraprocedural Guidance of TAVI in CHINA

Launched by XIJING HOSPITAL · Mar 21, 2025

Keywords

ClinConnect Summary

As the transcatheter aortic valve implantation (TAVI) procedure matures, complications such as paravalvular regurgitation (PVR), stroke, conduction disturbances, vascular complications, and annular rupture have been targeted for further improving the long-term outcome of TAVI. Paravalvular regurgitation (PVR) is associated with mortality following TAVI, even in those with mild PVR. Accurate procedural assessment of AR-critical for successful TAVI. Aortic root angiography, typically using Seller's visual grading, is the first screening tool used in most laboratories for the detection of post...

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Eligibility criteria

• Inclusion Criteria:
• • 1. Subject has aortic stenosis with indication of TAVI implantation as determined by Heart Team.
• • 2. Patient is at least 18 years of age.
• • 3. Signed informed consent. The patient understands and accepts clinical follow-up.
• Exclusion Criteria:
• • 1. Subject is not willing to provide an informed consent form, or whose legal heirs object to their participation in the study.
• • 2. If the patient is not suitable for participating in the study, based on the evaluation by the operators.
• • 3. Cardiogenic shock.
• • 4. Significant comorbidities precluding clinical follow-up (as judged by investigators).
• • 5. History of TAVI or SAVR.
• • 6. Renal insufficiency (GFR/MDRD \<45 ml/min), which precludes in operator's opinion contrast injection during repeat aortography.