Prognosis Analysis of Three Surgical Techniques for Arthroscopic Anterior Cruciate Ligament Reconstruction
Launched by BEIJING TSINGHUA CHANG GUNG HOSPITAL · Mar 17, 2025
Trial Information
Current as of July 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how different surgical techniques for reconstructing a torn anterior cruciate ligament (ACL) can affect recovery. The researchers are comparing three methods: Anatomical Single-Bundle Reconstruction (ASBR), Central Axial Single-Bundle Reconstruction (CASBR), and Double-Bundle Reconstruction (DBR). They want to understand how the way these tunnels are drilled during surgery impacts the healing process of the graft (the tissue used to replace the torn ligament) and ultimately, the outcome for patients after surgery.
To participate in this study, individuals must be between 18 and 50 years old and have a diagnosed ACL tear that occurred due to sports-related injuries. Participants should not have other ligament injuries or significant knee joint degeneration, and they should be able to commit to following the study's requirements. If you join the trial, you'll receive one of the surgical techniques being studied, and the researchers will monitor your recovery and how well the graft heals over time. This information will help improve surgical options for future patients with similar injuries.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Diagnosed with anterior cruciate ligament (ACL) rupture; Age between 18-50 years; All patients must have isolated anterior cruciate ligament (ACL) rupture; Knee joint degeneration \< KL grade II, and intraoperative cartilage injury \< ICRS grade III; All isolated ACL rupture patients must not have other ligament injuries; If accompanied by meniscus injury, the proportion of medial or lateral meniscus resection during surgery must not exceed 40%; The duration of the condition must be within one year after injury; No restriction on body weight; The cause of ACL rupture must be sports-related trauma or twisting injuries, excluding car accident injuries.
- Exclusion Criteria:
- • Patients with other surgical contraindications; Patients with poor compliance; Patients planning pregnancy; Patients deemed unsuitable for inclusion by the researchers.
About Beijing Tsinghua Chang Gung Hospital
Beijing Tsinghua Chang Gung Hospital is a leading medical institution in China, known for its commitment to advancing healthcare through innovative clinical research and trial sponsorship. Affiliated with Tsinghua University and Chang Gung Memorial Hospital, the facility combines cutting-edge medical technology with a robust academic framework to facilitate high-quality clinical trials. The hospital specializes in a range of therapeutic areas, focusing on improving patient outcomes and contributing to global medical knowledge. With a multidisciplinary team of experts, Beijing Tsinghua Chang Gung Hospital is dedicated to fostering collaborations that enhance the efficacy and safety of new treatments.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported