Circadian Rhythms in Human Adipose
Launched by MAYO CLINIC · Mar 21, 2025
Trial Information
Current as of April 23, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking to learn more about how our body's internal clock, known as circadian rhythms, affects fat tissue, particularly in people with obesity. Researchers want to see how these rhythms change when people eat continuously or follow regular eating patterns. By studying this, they hope to find better ways to understand and manage obesity.
The study is open to individuals aged 65 to 88 years, regardless of gender. To participate, you should have a body mass index (BMI) between 20-25 or 30-37 and, if you have obesity, your waist should be larger than your hips. Participants should be generally sedentary and not pregnant or breastfeeding. You will not be eligible if you have certain medical conditions, sleep issues, or if you smoke. If you join the study, you can expect to follow specific instructions and provide written consent to participate. This research could help uncover important information about how our bodies process fat and the impact of our eating habits.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • BMI 20-25 kg/m2 or 30-37 kg/m2
- • For participants with obesity a waist-to-hip ratio of ≥0.95 in males and ≥0.90 in females.
- • sedentary
- • females: non pregnant or breastfeeding
- • ability to provide written informed consent and follow study instructions
- Exclusion Criteria:
- • History of mediations that impact adipocyte/lipid metabolism
- • smoking
- • insomnia
- • sleep apnea
- • sleep medication use
- • employment in night or shift work
- • extreme chronotypes
- • Allergy to lidocaine
About Mayo Clinic
Mayo Clinic is a renowned nonprofit medical practice and research institution dedicated to providing comprehensive healthcare and advancing medical knowledge through innovative research and education. With a commitment to patient-centered care, Mayo Clinic conducts numerous clinical trials aimed at exploring new therapies and improving treatment outcomes across various disciplines. Leveraging a multidisciplinary approach, the institution collaborates with leading experts and cutting-edge technology to ensure rigorous scientific standards and ethical practices in all its research endeavors. Through its trials, Mayo Clinic seeks to translate breakthroughs in science into tangible benefits for patients, fostering advancements in medicine that enhance health and quality of life.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rochester, Minnesota, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported