Multicenter Prospective Observational Study on Diaphragmatic Function Assessment by Ultrasound in Patients with Acute Respiratory Failure Receiving Non-invasive Mechanical Ventilation or High Flow Nasal Canula
Launched by FORO INTERNACIONAL EN CUIDADO CRÍTICO · Mar 21, 2025
Trial Information
Current as of April 23, 2025
Not yet recruiting
Keywords
ClinConnect Summary
Protocol for Assessment and Measurement of Diaphragmatic Ultrasound
Ultrasonographic Evaluation of the Diaphragm Protocol:
This protocol focuses on observing and evaluating diaphragmatic function in patients with acute respiratory failure who require non-invasive mechanical ventilation (NIMV) and/or high-flow nasal cannula (HFNC). The ultrasound measurements performed by researchers will be standardized to ensure consistency and accuracy in assessing diaphragmatic function.
Assessment of Diaphragmatic Thickness Collection of arterial blood gases is performed 1 hour after being on the cli...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age ≥ 18 years
- • Hypoxemic respiratory failure (SpO2 \< 88% - PaO2 \< 60 mmHg) or hypercapnic (PaCO2 \> 40)
- • Need for NIMV and/or HFNC.
- Exclusion Criteria:
- • Neuromuscular disease
- • Pregnancy
- • Tracheostomy
- • Rib fractures
- • Cervical injuries
- • Diaphragmatic paralysis
- • Diaphragmatic malformations
- • Hemodynamic instability
- • Morbid obesity (BMI \> 35)
- • Use of sedation and neuromuscular relaxants
- • Pneumothorax or pneumomediastinum
- • Poor acoustic window
- • Critically ill patients with a prognosis of less than 24 hours of life Patients receiving palliative interventions.
Trial Officials
Carlos A Santacruz H, MD, PhD
Study Director
Foro Internacional en Cuidado Crítico
About Foro Internacional En Cuidado Crítico
Foro Internacional en Cuidado Crítico is a leading organization dedicated to advancing the field of critical care through innovative research and clinical trials. Committed to improving patient outcomes and enhancing the quality of care, the organization fosters collaboration among healthcare professionals, researchers, and institutions globally. By focusing on evidence-based practices and cutting-edge methodologies, Foro Internacional en Cuidado Crítico aims to address the complex challenges faced in critical care settings, ultimately contributing to the development of effective treatment protocols and improving healthcare delivery for critically ill patients.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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