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Search / Trial NCT06893055

Strength-Endurance Circuit Training in Parkinson's Disease

Launched by GENERAL UNIVERSITY HOSPITAL, PRAGUE · Mar 18, 2025

Trial Information

Current as of July 09, 2025

Recruiting

Keywords

Parkinson Disease Strength Training Endurance Training Physiotherapy Irisin Quality Of Life Physical Performance

ClinConnect Summary

This clinical trial is studying whether adding strength training to regular aerobic exercise can improve the health and quality of life for people with Parkinson's disease, compared to just doing aerobic exercise alone. Researchers want to see if this combined training helps with physical performance, disease severity, and even certain blood markers related to health. Participants will take part in training sessions twice a week for 12 weeks, and their progress will be measured before and after the training, as well as three months later. Some selected participants will also receive a smartwatch to track their steps throughout the study.

To be eligible for this trial, participants must be at least 18 years old and have a diagnosis of idiopathic Parkinson's disease. They should also be stable on their Parkinson's medication and have a certain level of disease severity. However, those who are 75 years or older, have more advanced stages of Parkinson's, or have specific movement issues will not be able to participate. This study offers a chance to explore new ways to manage Parkinson's symptoms and improve overall well-being.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age ≥18 years
  • diagnosis of idiopathic Parkinson´s disease
  • Hoehn-Yahr Scale ≤ 2,5
  • stable dopaminergic medication
  • Exclusion Criteria:
  • age ≥75 years
  • Hoehn-Yahr Scale ≥ 2,5
  • deep brain stimulation
  • presence of freezing
  • Camptocormia
  • inability to walk without support
  • inability to perform study procedures
  • limiting co-morbidities
  • attendance at training sessions below 70%

About General University Hospital, Prague

General University Hospital in Prague is a leading academic medical institution dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital leverages its multidisciplinary expertise and state-of-the-art facilities to facilitate cutting-edge studies across various therapeutic areas. Committed to improving patient outcomes and contributing to the global medical community, the hospital collaborates with various stakeholders, including academic partners, pharmaceutical companies, and regulatory bodies, to ensure the highest standards of clinical research. Its focus on ethical practices and patient safety underscores its role as a trusted leader in clinical trial sponsorship.

Locations

Prague, , Czech Republic

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported