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Search / Trial NCT06893614

Facial Conformation Meshes for Orthognathic Surgery

Launched by AIN SHAMS UNIVERSITY · Mar 23, 2025

Trial Information

Current as of August 22, 2025

Recruiting

Keywords

Orthognathic Surgery Three Dimensional Imaging. Soft Tissue. Cone Beam Computed Tomography Prognathism Treatment Outcome Computer Simulation

ClinConnect Summary

This clinical trial is studying a new way to predict how a patient's face will look after undergoing a specific type of jaw surgery known as bimaxillary orthognathic surgery. This procedure is often performed on individuals with Class III dentofacial deformities, where the jaw alignment can affect both appearance and function. The researchers are using advanced 3D imaging technology to improve the accuracy of these predictions, which could help doctors plan surgeries more effectively and achieve better outcomes for their patients.

To participate in the study, individuals must have had certain types of jaw surgery and provide preoperative and at least six months postoperative 3D scans of their face. However, those with specific conditions, such as previous facial surgeries, certain craniofacial anomalies, or significant facial asymmetry, will not be included. The study uses existing imaging data, so no new procedures will be performed for this trial, and participants' privacy will be protected throughout the process. The findings from this research aim to enhance our understanding of facial changes after surgery and improve the overall treatment planning in maxillofacial surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Preoperative and at least 6 months postoperative CBCTs of Patients who suffered from class III facial deformity and had bimaxillary orthognathic surgical correction who undergone maxillary advancement and mandibular setbacks.
  • Exclusion Criteria:
  • * CBCTs of patients with:
  • Craniofacial anomalies including cleft lip/palate,
  • who had had previous maxillofacial operations or facial scars,
  • Surgical Corrections that required multi-segment Le Fort I osteotomies,
  • Simultaneous Genioplasty as part of the carried-out corrections.
  • Significant facial Asymmetry.
  • Missing Data

About Ain Shams University

Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.

Locations

Cairo, Abbassia, Egypt

Abbassia, Cairo, Egypt

Patients applied

0 patients applied

Trial Officials

Ashraf F Ayoub, Professor

Study Chair

Department of Oral and Maxillofacial Surgery, School of Medicine, Dentistry & Nursing, Glasgow Dental Hospital & School, Glasgow, United Kingdom.

Mohammed Diaa Zain El Abedeen, Professor

Study Director

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt

Nehal I Shobair, Lecturer

Principal Investigator

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Misr International University, Cairo, Egypt

Xiangyang Ju, Head of Image Processing

Study Director

Medical Devices Unit, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom

Amr A Ghanem, Professor

Study Director

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt

Amr M Ekram, Consultant

Study Director

Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University

Ahmed Barakat, Professor

Study Director

Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported