Facial Conformation Meshes for Orthognathic Surgery
Launched by AIN SHAMS UNIVERSITY · Mar 23, 2025
Trial Information
Current as of August 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new way to predict how a patient's face will look after undergoing a specific type of jaw surgery known as bimaxillary orthognathic surgery. This procedure is often performed on individuals with Class III dentofacial deformities, where the jaw alignment can affect both appearance and function. The researchers are using advanced 3D imaging technology to improve the accuracy of these predictions, which could help doctors plan surgeries more effectively and achieve better outcomes for their patients.
To participate in the study, individuals must have had certain types of jaw surgery and provide preoperative and at least six months postoperative 3D scans of their face. However, those with specific conditions, such as previous facial surgeries, certain craniofacial anomalies, or significant facial asymmetry, will not be included. The study uses existing imaging data, so no new procedures will be performed for this trial, and participants' privacy will be protected throughout the process. The findings from this research aim to enhance our understanding of facial changes after surgery and improve the overall treatment planning in maxillofacial surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Preoperative and at least 6 months postoperative CBCTs of Patients who suffered from class III facial deformity and had bimaxillary orthognathic surgical correction who undergone maxillary advancement and mandibular setbacks.
- Exclusion Criteria:
- * CBCTs of patients with:
- • Craniofacial anomalies including cleft lip/palate,
- • who had had previous maxillofacial operations or facial scars,
- • Surgical Corrections that required multi-segment Le Fort I osteotomies,
- • Simultaneous Genioplasty as part of the carried-out corrections.
- • Significant facial Asymmetry.
- • Missing Data
About Ain Shams University
Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, Abbassia, Egypt
Abbassia, Cairo, Egypt
Patients applied
Trial Officials
Ashraf F Ayoub, Professor
Study Chair
Department of Oral and Maxillofacial Surgery, School of Medicine, Dentistry & Nursing, Glasgow Dental Hospital & School, Glasgow, United Kingdom.
Mohammed Diaa Zain El Abedeen, Professor
Study Director
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt
Nehal I Shobair, Lecturer
Principal Investigator
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Misr International University, Cairo, Egypt
Xiangyang Ju, Head of Image Processing
Study Director
Medical Devices Unit, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom
Amr A Ghanem, Professor
Study Director
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt
Amr M Ekram, Consultant
Study Director
Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University
Ahmed Barakat, Professor
Study Director
Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported