Electroencephalogram Predicts Post-operative Delirium

Launched by BEIJING SANBO BRAIN HOSPITAL · Mar 18, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating whether a specific type of brain monitoring called sub-hairline electroencephalography (EEG) can help predict if patients will experience confusion or delirium after undergoing brain surgery. Delirium is a common issue that can happen after surgery, and the researchers want to see if monitoring brain activity right after anesthesia can give clues about who might be at risk for this condition. The study will include adult patients who are scheduled for elective brain surgery and will be monitored in the Intensive Care Unit (ICU) until they are ready to go home.

To participate in this trial, patients need to be at least 18 years old and scheduled for a planned brain surgery. They also need to be in relatively good health, as defined by specific criteria. However, individuals with certain neurological or psychiatric conditions, pre-existing cognitive issues, or those who have had recent brain surgery may not be eligible. Participants can expect to have their brain activity monitored during their recovery, which will help researchers gather important information about the connection between brain activity and postoperative delirium. Overall, this study aims to improve understanding and management of delirium after brain surgery, ultimately enhancing patient care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Planned elective neurosurgical surgery
• • ASA physical status I-II
• • Signed informed consent
• Exclusion Criteria:
• • Known neurological or psychiatric disorders (e.g., epilepsy, Parkinson's disease)
• • Preoperative cognitive impairment (MMSE score \< 24)
• • Long-term use of central nervous system drugs (e.g., antidepressants, antipsychotics)
• • Language barriers
• • History of craniotomy within the last 12 months
• • Inability to place frontal-temporal electrodes due to conditions such as frontal skin injury, severe agitation, or a coronal incision for surgery
• • Pregnant or breastfeeding women