Tegoprazan and Lansoprazole Effectiveness in Bleeding Peptic Ulcer Treatment

Launched by MARIO STEFFANUS · Mar 19, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two medications, tegoprazan and lansoprazole, to see which one works better for healing bleeding peptic ulcers. Peptic ulcers are sores in the stomach or the first part of the intestine that can cause bleeding. The goal is to find out how well each drug helps patients heal over two weeks and to check for any side effects. Participants will take either tegoprazan or lansoprazole every day for two weeks, and doctors will examine their ulcers before and after the treatment to see how well they have healed.

To join the study, participants should be adults aged 65 to 74 who have been diagnosed with bleeding from a peptic ulcer through a stomach examination. However, those who are allergic to either medication, have certain serious health conditions, or are currently pregnant cannot participate. This trial is still looking for volunteers, and it aims to provide valuable information about the best treatments for peptic ulcer bleeding.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Subjects diagnosed with upper gastrointestinal bleeding caused by peptic ulcer through gastroscopic examination
• Exclusion Criteria:
• • Allergic to Tegoprazan or Lansoprazole, diagnosed with gastric or duodenal cancer, pregnant, history of H. pylori infection treatment failure, presence of comorbidities such as chronic kidney disease or decompensated liver cirrhosis, alcohol consumption, or undergoing chemotherapy.