Effectiveness and Safety of Limbal Relaxing Incisions for Correcting Post Phacoemulsification High Astigmatism
Launched by ASSIUT UNIVERSITY · Mar 24, 2025
Trial Information
Current as of July 24, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at a treatment called Limbal Relaxing Incisions (LRIs) to see how effective it is for correcting high astigmatism that can occur after cataract surgery (phacoemulsification). The study aims to find out if combining LRIs with glasses improves vision better than just using glasses alone.
To participate in this trial, you should be between the ages of 65 and 74 and have had cataract surgery at least a month ago. You must also have a clear cornea and have astigmatism greater than 3.0 diopters, which is a measure of how distorted your vision is. However, if you have had previous eye surgeries, experienced eye injuries, or have certain eye diseases, you may not be eligible. If you join the study, you can expect to have your vision monitored to see how well the treatment works compared to just wearing glasses. It’s an opportunity to help understand a new approach to improving vision after cataract surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Conventional phacoemulsification was done at least one month earlier.
- • Clear cornea with corneal astigmatism more than 3.0 D.
- Exclusion Criteria:
- • History of corneal surgeries (e.g., keratoplasty, refractive surgery, and corneal wound repair).
- • Ocular trauma.
- • Other intraocular surgery.
- • Patient with corneal opacities.
- • Thin cornea .
- • Any significant ocular disease causing diminution of vision (e.g., optic atrophy, diabetic retinopathy, and age-related macular degeneration), autoimmune disease, and peripheral corneal disease.
About Assiut University
Assiut University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that enhance healthcare outcomes. With a strong emphasis on innovation and collaboration, the university engages in a wide array of clinical studies across various disciplines, aiming to contribute valuable insights into disease prevention, diagnosis, and treatment. Assiut University's commitment to ethical research practices and rigorous scientific methodology ensures the integrity and reliability of its clinical trials, ultimately benefiting both the local community and the global medical landscape.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Ehab Ismail Ahmed, Professor
Study Chair
Assiut University
Hani Omar Elsodafy, Assistant Professor
Study Chair
Assiut University
Sara Hussein Mohamed, Lecturer
Study Director
Assiut University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported