DEciphering CIrculating SIgnatures Of Infected Pancreatic Necrosis

Launched by UNIVERSITY OF MINNESOTA · Mar 20, 2025

Keywords

ClinConnect Summary

The DEciphering CIrculating SIgnatures Of Infected Pancreatic Necrosis clinical trial aims to find new blood tests that can help doctors predict and diagnose infected pancreatic necrosis (IPN) in patients suffering from a severe form of acute pancreatitis known as necrotizing pancreatitis (NP). Acute pancreatitis is a painful and serious condition that leads to inflammation and damage in the pancreas, and in some cases, it can progress to NP, where parts of the pancreas start to die. If this dead tissue gets infected, it can lead to serious complications, including organ failure and a high risk of death. Currently, it can be difficult for doctors to tell if a patient has an infection or not, which can delay important treatments.

To participate in this trial, you need to be an adult over 18 years old and have been diagnosed with necrotizing pancreatitis through a specific imaging test. Unfortunately, those with certain conditions, such as pancreatic cancer or immunodeficiency disorders, will not be eligible. If you join the study, you can expect to provide blood samples that researchers will use to identify potential new biomarkers, or indicators, of IPN. These findings could help improve how doctors diagnose and treat patients with this serious condition in the future. The trial is not yet recruiting participants, but it represents a step forward in understanding and managing a challenging health issue.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults aged \>18 years.
• • Diagnosis of NP based on CECT.
• Exclusion Criteria:
• • recurrent AP
• • pancreatic cancer
• • pregnancy, lactation
• • solid organ transplant
• • immunodeficiency disorders like AIDS.