#AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial.

Launched by CASPER ROKX · Mar 22, 2025

Keywords

ClinConnect Summary

The #AWARE.HIV Europe trial is a study aimed at improving how often hospitals test patients for HIV, especially those showing symptoms or conditions that may indicate HIV. This trial will involve hospitals from ten European countries and will introduce specialized HIV teams in these hospitals to help increase testing rates. These teams, led by HIV specialists, will work to identify patients who need testing, provide education to healthcare workers, and streamline the testing process to make it easier and less stigmatized for everyone involved.

To participate in this trial, hospitals need to meet several criteria, including having the necessary resources and management approval to create an HIV team and integrate testing into their routine care. While this study is not yet recruiting participants, it aims to gather valuable information that could lead to better early diagnosis and treatment of HIV, ultimately helping to reduce the number of new HIV cases and improve health outcomes for patients across Europe.

Gender

ALL

Eligibility criteria

• • Since this study involves screening individuals presenting to a specific hospital through a hospital-wide intervention, the inclusion and exclusion criteria are established at the hospital level.
• Inclusion Criteria:
• • 1. Standard of care: HIV testing for HIV indicator conditions should be part of routine care in the country, and any prevailing guidelines on HIV testing and prevention policies can be integrated.
• • 2. Management approval: Hospital management must be willing to allocate resources and provide authorization for the proposed activities, including Surveillance, Audit \& Feedback, Education \& Training, Linkage to Prevention, and fostering an Enabling Environment, including stigma reduction.
• • 3. Resources: Assembling an HIV team led by a local HIV expert should be viable considering the available human resources.
• • 4. Data collection: There should be an IT specialist and IT infrastructure capable of flagging a pre-defined set of HIV indicator conditions and monitoring the project's implementation effects with feedback loops to healthcare professionals.
• • 5. Quality assurance: Continuous linkage for care and access to antiretroviral therapy must be assured.
• • 6. Ethics and Regulatory Compliance: Provision for ethical and regulatory compliance is necessary.
• Exclusion Criteria:
• • Any hospital that does not meet the inclusion criteria will be excluded from participation. We will not use data of patients who have objected against the use of their data for research.