Reconstruction of Deficient Maxillary Ridges Using Retromolar Blocks With and Without Collagen Membrane

Launched by CAIRO UNIVERSITY · Mar 22, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two different methods for improving bone in the upper jaw, also known as the maxilla, specifically in areas where there has been bone loss. The study will compare the use of a collagen membrane placed over a special mixture of bone particles and an onlay bone block, against using just the bone mixture and onlay block without the collagen membrane. The goal is to see if the collagen membrane helps create more bone in the area.

To participate in this trial, individuals must be at least 18 years old and have enough remaining bone height and width in their jaw to support the procedure. This includes people who have lost at least one tooth and may have had issues with previous dental implants or bone grafts. However, individuals who smoke heavily, abuse alcohol or drugs, have certain medical conditions, or are pregnant will not be eligible. If you join the study, you can expect to receive either of the two treatment methods, and the research team will monitor your progress to see how well the bone develops over time.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with maxillary residual alveolar bone height not less than 8 mm.
• • Alveolar bone width from less than or equal 5 mm.
• • Both genders.
• • At least missing single tooth.
• • Previous Failed Implants.
• • Previous Failed Grafting.
• Exclusion Criteria:
• • • Heavy smokers more than 20 cigarettes per day.
• • Patients with alcohol abuse
• • Patients with narcotic abuse.
• • Patients with bone disease that may affect normal healing, example; hyperparathyroidism.
• • Patients had radiotherapy and chemotherapy in head and neck.
• • Patients had neoplasms in sites to be grafted.
• • Patients with Metabolic diseases uncontrolled diabetic patients, Glycated hemoglobin (Hb A1c) more than 7 mg\\dl.
• • Pregnant females.
• • Patients with Para functional habits, apprehensive and non-cooperative.
• • Bone pathology related to the site to be grafted.
• • Psychological problems, stress situation (socially or professionally), emotional instability, and unrealistic patients' expectations.
• • Intraoral soft and hard tissue pathology.
• • Systemic condition that contraindicate implant placement.
• • Under the age of 18 years.