Trial Information
Current as of July 23, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial, called Graded Exercise Hypoxia Testing, is looking to understand how well different people cope with low oxygen levels during exercise. The researchers want to develop a standardized test that gradually increases exercise intensity while reducing oxygen availability. By studying factors like breathing response, heart rate, and overall lung health, they hope to find out why some people can handle exercise in low-oxygen conditions better than others. This information could help create better treatments for people who struggle with exercising in such conditions.
To participate in this study, you need to be physically active, engaging in at least 150 minutes of moderate exercise each week. However, there are some important restrictions: you cannot have certain health issues, such as serious heart or lung problems, and you should not be pregnant or have a body mass index (a measure of body fat) that is too low or too high. If you qualify and decide to join, you can expect to undergo a series of exercise tests while your body’s responses are monitored. Your participation could contribute to valuable insights that may help improve health for many people in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • • Physically active (≥150 minutes of moderate physical activity per week)
- Exclusion Criteria:
- • Contraindications to exercise testing
- • Currently pregnant
- • Musculoskeletal or metabolic disease
- • Allergies to lidocaine
- • Body-mass index ≤18 or ≥35 kg·m-2
- • Pacemaker
- • No confounding cardiorespiratory disease
- • Persistent tobacco use (\>15 pack years)
About Mayo Clinic
Mayo Clinic is a renowned nonprofit medical practice and research institution dedicated to providing comprehensive healthcare and advancing medical knowledge through innovative research and education. With a commitment to patient-centered care, Mayo Clinic conducts numerous clinical trials aimed at exploring new therapies and improving treatment outcomes across various disciplines. Leveraging a multidisciplinary approach, the institution collaborates with leading experts and cutting-edge technology to ensure rigorous scientific standards and ethical practices in all its research endeavors. Through its trials, Mayo Clinic seeks to translate breakthroughs in science into tangible benefits for patients, fostering advancements in medicine that enhance health and quality of life.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rochester, Minnesota, United States
Rochester, Minnesota, United States
Patients applied
Trial Officials
Michael Joyner, M.D.
Principal Investigator
Mayo Clinic
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported