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Search / Trial NCT06902922

Impact of Severe Tricuspid Regurgitation Correction on Gut Microbiota and Gastrointestinal Function

Launched by FRANCESCO MAISANO · Mar 24, 2025

Trial Information

Current as of April 23, 2025

Not yet recruiting

Keywords

Tricuspid Regurgitation Gut Microbiota Gastrointestinal Heart Heart Valve Disease Tricuspid Valve Disease Transcatheter T Teer

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult patients, able to sign the Informed Consent Form, admitted to OSR Heart Valve Center with TR ≥ severe treated with T-TEER.
  • Exclusion Criteria:
  • Concomitant ≥ severe MR. Such patients may be treated with M-TEER and be re-evaluated after 3 months: if TR is ≥ severe and MR is ≤ moderate the patient may then be enrolled.
  • Surgical candidates
  • Recent \< 6 months cardiac coronary or structural procedure
  • CAD requiring intervention
  • other valvular disease \> moderate
  • Treatment with transcatheter tricuspid replacement
  • Age \<18 years
  • Inability or unwillingness to sign informed consent
  • Kidney dialysis
  • Acute infection
  • Inflammatory bowel diseases
  • Gastrointestinal diseases
  • Previous gastrointestinal surgery
  • Active cancer
  • Active autoimmune or inflammatory diseases
  • Treatments with antibiotics or probiotics within one month
  • Emergency procedures
  • Patients enrolled in interventional studies that may confound study results

About Francesco Maisano

Francesco Maisano is a distinguished clinical trial sponsor with a commitment to advancing medical research and innovation. With extensive expertise in the field, he oversees the design and implementation of clinical studies aimed at evaluating new therapies and interventions. His leadership is characterized by a strong emphasis on ethical standards, regulatory compliance, and patient safety, ensuring that all trials are conducted with the highest integrity. Under his guidance, the organization strives to foster collaboration among research teams, healthcare professionals, and stakeholders, ultimately contributing to the enhancement of patient care and outcomes in various therapeutic areas.

Locations

Milano, , Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported