Experience of Biologic Treatments for Severe Asthma: a Survey

Launched by ROYAL DEVON AND EXETER NHS FOUNDATION TRUST · Mar 25, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring the experiences of patients with severe asthma who are receiving biologic treatments. Severe asthma can cause serious breathing problems and affect many areas of life, leading to feelings of isolation, anxiety, and depression. While there are several biologic treatments available that have improved how severe asthma is managed, researchers want to understand how these treatments impact patients' daily lives beyond just clinical measurements like lung function. The trial will gather insights from patients about their experiences, including how well the treatments work for them, any side effects they may have, and how these treatments affect their overall quality of life.

To participate in the trial, individuals must be receiving a biologic treatment for at least 6 months but no longer than 18 months. Participants should not have switched treatments recently and must be in a position to provide consent for their data to be used. The survey has been carefully designed with input from patients themselves, ensuring that it captures important experiences in clear language. By taking part, patients can help researchers better understand the varied responses to biologic treatments for severe asthma, which could lead to improved care and support for others in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Receiving a biologic treatment for at least 6 months.
• • • But has not been on the treatment for longer than 18 months. Note: In clinical practice, a 12-month trial of biologic treatments is needed before a decision to stop/switch treatment is made. Therefore, our inclusion criteria will capture people who are non-responders to biologic treatments.
• Exclusion Criteria:
• • Patients will be excluded if they are unwilling/unable to provide consent to use their data.
• • Patients who have switched biologics will also be excluded.
• • In the opinion of the physician responsible for the care of the patient, the patient has a condition, other than asthma which is significantly contributing to their respiratory symptoms, e.g. lung cancer, heart failure or severe COPD.