Mechanisms of Brain-Heart Injury of Post-Intracranial Hemorrhage

Launched by BEIJING TIANTAN HOSPITAL · Mar 29, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of intracranial hemorrhage, which is bleeding in the brain, on both brain and heart health. Specifically, researchers want to understand how this type of bleeding can lead to injuries in the brain and heart. They are looking for patients who are 18 years or older and have had a confirmed case of intracranial hemorrhage within the last 48 hours. Participants will receive standard medical treatment and undergo various tests to help researchers learn more about the connections between brain injuries and heart problems, which can sometimes happen together.

If you or a loved one is eligible and decides to join the study, you can expect to receive careful monitoring and a thorough evaluation of your health. The goal is to improve understanding of how these injuries occur and to help doctors make better decisions when treating patients with similar conditions in the future. It’s important to note that some individuals with certain heart conditions or recent surgeries may not be able to participate for safety reasons.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients aged 18 years or older at the time of enrollment.
• • 2. Acute intracranial hemorrhage confirmed by neuroimaging (CT, MRI，CTA, MRA, or DSA) within 48 hours of symptom onset.
• • 3. Ability to provide informed consent or have a legally authorized representative willing to consent on their behalf.
• Exclusion Criteria:
• • 1. Patients who refuse to participate in the study or cannot provide informed consent.
• • 2. Patients with a history of significant cardiovascular disease, including myocardial infarction, heart failure, or arrhythmias, unless stable and well-controlled.
• • 3. Patients who have undergone cardiac bypass surgery, stent placement, or other cardiovascular interventions within the past 6 months.
• • 4. Patients with active brain tumors, ischemic stroke within 3 months or a history of previous brain injury that could confound the study findings.
• • 5. Patients with active malignant disease, severe inflammatory or infectious disease, or those who have undergone surgery for any reason within the past 3 months.
• • 6. Patients with any condition that, in the opinion of the investigator, would make it unsafe or impractical to participate in the study.