Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)

Launched by ADVENTHEALTH TRANSLATIONAL RESEARCH INSTITUTE · Apr 2, 2025

Keywords

ClinConnect Summary

The ACCESS-T1D trial is a study aimed at finding people with Type 1 Diabetes (T1D) or Celiac Disease (CD) early in their illness, so they can get help sooner. The researchers are working to improve the ways we screen for these conditions, which can lead to better care and outcomes for patients. The trial is currently looking for participants, including children over the age of 2 and adults at risk of developing T1D. To qualify, participants should have a family history of T1D, other autoimmune diseases, or specific types of diabetes that might be misdiagnosed as T1D.

If you or a loved one is interested in joining the study, you will need to live in specific counties in Florida, such as Orange or Seminole. Participants will be asked to provide consent, and those under 18 will need permission from a parent or guardian. Throughout the study, participants can expect to undergo routine screenings and assessments related to their health. This trial will not include individuals already diagnosed with advanced T1D or those who have had an organ transplant. Joining this study could help researchers better understand and manage these diseases, leading to improved healthcare for everyone affected.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • 1. Able to provide informed consent (adults 18 and above) and assent if seven or above. Legally authorized representative (LAR) is able to provide consent in case of minors or in case of adults unable to consent.
• 2. Children \> 2 years and adults at elevated risk of developing (or having misdiagnosed) clinically evident Stage 3 T1D because they have at least one of the following:
• • i. have one or more first- or second-degree family members (siblings, parents, cousins, aunts/uncles, grandparents) diagnosed with type 1 diabetes or ii. have other autoimmune diseases such as but not limited to celiac disease, Multiple sclerosis, rheumatoid arthritis or, thyroid disease or iii. Those diagnosed with other forms of diabetes which are suspected of being T1D because of a BMI ≤28 or progression to insulin dependence within 3 years from diagnosis.
• • 3. Resides in the following Counties: Orange, Seminole, Osceola, Lake, Volusia, Brevard, Polk, Hillsborough.
• • Exclusion Criteria
• • 1. People with a diagnosis of type stage 3T1D or T1D clinical definition per ADA Standards of Care
• • 2. History of organ transplant
• • 3. Be deemed unable or unlikely to comply with the protocol.
• • 4. Presence of any condition that, in the opinion of the Investigator, compromises participant safety or data integrity or the participant's ability to complete study visit/s.