Clinical Characterization of Very and Extremely Preterm Infants Who Received Excess Erythrocyte Transfusions With Respect to HAS 2014 Recommendations

Launched by CENTRE HOSPITALIER UNIVERSITAIRE, AMIENS · Mar 27, 2025

Keywords

ClinConnect Summary

This clinical trial is studying very and extremely premature infants, specifically those who have received extra blood transfusions. Premature babies, born before 31 weeks of pregnancy, often face severe anemia, which means they don't have enough red blood cells to carry oxygen in their bodies. To help these infants, doctors use blood transfusions, but sometimes they give more transfusions than recommended, which can lead to side effects. The trial aims to understand how often this happens and why, using data from babies born at the CHU Amiens-Picardie hospital between July 2022 and July 2024.

To participate in this study, babies need to be less than 28 days old and have been born before 31 weeks of pregnancy, receiving care at the hospital’s intensive care unit. Unfortunately, babies born at 31 weeks or later, or those older than 28 days, cannot join. Families of eligible infants can expect their baby's transfusion records to be reviewed to see if they follow the recommended guidelines. This study is important because it can help improve the care of premature infants by ensuring that blood transfusions are given safely and effectively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age : ≤ 28 days of life
• • Premature newborn with term of birth \< 31 weeks hospitalized in intensive care or neonatology intensive care at CHU Amiens-Picardie (CHU-AP) between July 2022 and July 2024, whether born at CHU-AP maternity unit or transferred secondarily
• Exclusion Criteria:
• • Newborn with term of birth ≥ 31 weeks and \> 28 days of life