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Search / Trial NCT06909916

Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures

Launched by LONDON HEALTH SCIENCES CENTRE RESEARCH INSTITUTE OR LAWSON RESEARCH INSTITUTE OF ST. JOSEPH'S · Mar 27, 2025

Trial Information

Current as of July 09, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging technique called weight-bearing CT to see how well it can assess healing in patients who have experienced a specific type of fracture around their knee implant, known as a periprosthetic fracture. After having knee replacement surgery, some patients may suffer from these fractures, which can complicate their recovery. This study aims to improve the way doctors evaluate bone healing and alignment in these patients, potentially leading to better treatment outcomes and fewer surgeries in the future.

To participate, individuals need to be between 50 and 90 years old and have had revision surgery for a specific type of knee fracture related to their knee implant. They should also have a body mass index (BMI) of up to 40 and be able to provide informed consent, meaning they understand the study and agree to take part. During the trial, participants will undergo CT scans while standing and sitting to check their bone healing and report any pain they feel. By taking part in this study, individuals can contribute to improving care for others in similar situations.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Underwent revision surgery for repair of a distal femur fracture surrounding a primary TKA femoral component using a fracture fixation plate \>1 year
  • Age 50-90 years
  • Body mass index up to 40kg/m2
  • Able to provide informed consent
  • Able and willing to do study assessments and follow instructions
  • Exclusion Criteria:
  • Does not understand English
  • Undergone revision surgery for any other indication
  • Received Intramedullary nail or distal femur replacement
  • Cannot independently stand on one leg in the weight-bearing CT during the inducible displacement exam

About London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's

The London Health Sciences Centre Research Institute, affiliated with Lawson Health Research Institute at St. Joseph's Health Care, is dedicated to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into practical applications, the institute fosters collaboration among leading researchers, clinicians, and healthcare professionals. It aims to improve patient outcomes and enhance the quality of care through rigorous investigation in areas such as cancer, cardiovascular health, and neuroscience. By integrating cutting-edge research with clinical practice, the institute plays a pivotal role in shaping the future of healthcare delivery in the community and beyond.

Locations

London, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Matthew Teeter, PhD

Study Director

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Brent Lanting, MD

Principal Investigator

Lawson Health Sciences Centre

Lyndsay Somerville, PhD

Study Chair

London Health Sciences Centre

Patrick J Mixa, MD

Study Chair

Western University

James Howard, MD

Study Chair

London Health Sciences Centre

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported