Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers

Launched by BRITISH UNIVERSITY IN EGYPT · Mar 28, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different treatments for a common oral condition called aphthous ulcers, which are small, painful sores in the mouth. The trial involves two groups of patients: one group will use an oxygenated gel, applying it directly to the sore twice a day for a week, while the other group will use a medicated paste called triamcinolone acetonide, applying it four times a day for the same duration. Researchers will check on all participants at various points after treatment to see how well each method works.

To participate in this trial, patients need to have a single aphthous ulcer that is less than 6 mm in size and should be generally healthy without any serious medical conditions. They must also provide written consent to join the study. It's important to note that this trial is looking for patients who do not have a history of certain other health issues, such as major forms of ulcers or herpetic lesions, and it excludes pregnant or breastfeeding individuals. If you're interested in participating, you can expect to receive detailed instructions on how to use the treatments and have follow-up visits to monitor your progress.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Clinically diagnosed patients with chronic aphthous stomatitis measuring ≤6 mm in size in the oral cavity and who gave written consent for participation.
• • Only single ulcers were considered for the study.
• • Systemically healthy patients.
• Exclusion Criteria:
• • The study excluded patients with a history of associated systemic disease.
• • Cases of chronic aphthous stomatitis (major), lesions of herpetic form, numerous aphthae, and smoking.
• • Patients with a history of hypersensitivity to the used agents.
• • Pregnancy and lactation