The Effect of Time Restricted Eating on Glycemic and Proinflammatory Biomarkers Among Prediabetic Obese Jordanian Adults Aged 18-40 Years Old
Launched by UNIVERSITY OF JORDAN · Mar 27, 2025
Trial Information
Current as of July 04, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how different eating patterns can affect health in young adults who are overweight and at risk of diabetes. Specifically, it looks at "time-restricted eating" (where you only eat during certain hours of the day) combined with calorie restriction, time-restricted eating without calorie limits, and calorie restriction without time limits. The goal is to see how these methods influence blood sugar control and inflammation in the body, which are important factors in preventing obesity-related health issues.
To participate, individuals must be between 18 and 40 years old, have a body mass index (BMI) of 30 to 39.9 (which indicates obesity), and have been diagnosed with insulin resistance, a condition where the body doesn't use insulin well. Participants should have maintained a stable weight for three months before starting the study and should not be physically active. Throughout the 12-week trial, participants will have their weight, body measurements, and blood tests checked regularly to track any changes. This research aims to find effective ways to help prevent serious health problems like type 2 diabetes.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • IR individuals diagnosed with IR by the physicians as indicated by HOMA-IR score
- • female and male, BMI ≥ 30 to 39.9 kg/m2
- • age between 18 and 40 years
- • stable weight for 3 months before the beginning of the study
- • sedentary lifestyle
- Exclusion Criteria:
- • previous weight loss surgery
- • pregnancy or intent to become pregnant
- • breastfeeding
- • chronic diseases
- • drug therapies that could interfere with the effectiveness of the dietary intervention (e.g., use of corticosteroids, and anti-diabetic drugs)
- • diabetic type 1 and 2 individuals
- • anyone physically active to reduce the influence of confounding covariates
About University Of Jordan
The University of Jordan, a leading institution in higher education and research in the region, is dedicated to advancing medical knowledge and improving healthcare outcomes through innovative clinical trials. With a commitment to ethical research practices and collaboration with various stakeholders, the University of Jordan aims to contribute significantly to the field of medicine by exploring new treatments and interventions. Its robust infrastructure and expertise in diverse health-related disciplines enable the university to conduct high-quality studies that address pressing health challenges, ultimately enhancing patient care and fostering scientific discovery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Amman, , Jordan
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported