FET in Adenomyosis

Launched by INDIRA IVF HOSPITAL PVT LTD · Mar 29, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how well two different treatments can help women with a condition called adenomyosis become pregnant after using frozen embryos. Specifically, the trial aims to see if combining a medication called a GnRH agonist with another drug called letrozole is more effective than using the GnRH agonist alone. The main goal is to determine which treatment leads to a higher pregnancy rate after 12 weeks of pregnancy.

To participate in this trial, women need to be diagnosed with adenomyosis through a specific ultrasound test and have a history of infertility that requires the use of frozen embryos. They must also have at least one good-quality frozen embryo available for transfer. However, women with certain health conditions or a higher body weight may not be eligible. The trial is not yet recruiting participants, but if you meet the criteria, it could be an opportunity to explore potential treatments that may improve pregnancy outcomes.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of adenomyosis confirmed via transvaginal ultrasound as per MUSA criteria History of infertility requiring frozen embryo transfer (FET). Availability of at least one good-quality frozen embryo for transfer
• Exclusion Criteria:
• • BMI ≥ 30 kg/m2 Presence of endocrine disorders; (uncontrolled diabetes mellitus, / hyperprolactinemia, thyroid dysfunction, Congenital adrenal hyperplasia, Cushing syndrome, or polycystic ovary syndrome Previous major uterine surgery Gestational carrier Fertility preservation