Evaluation of a Dimensional Adaptation of Good Psychiatric Management (GPM-extended) for the Treatment of Borderline Personality Disorder

Launched by ADDIPSY · Mar 31, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment approach for adults with borderline personality disorder (BPD) called GPM-extended. This method builds on an existing treatment known as Good Psychiatric Management (GPM) but adds personalized elements to better address individual needs and challenges. The main goal is to see if GPM-extended can reduce BPD symptoms more effectively than classic GPM over one year of treatment. Researchers will compare two groups of patients: one group will receive the GPM-extended treatment, and the other will receive classic GPM, both through weekly outpatient care. Throughout the year, patients will be evaluated at different points to assess their symptoms and overall well-being.

To participate in this trial, individuals must be at least 18 years old and have a diagnosis of borderline personality disorder. They need to agree to participate and be covered by the French national health insurance system. Those with certain serious mental health issues, like psychotic disorders or severe substance use problems, will not be eligible. Participants can expect to meet regularly with healthcare professionals, complete questionnaires, and receive support tailored to their needs. This study aims to improve treatments for personality disorders and help people lead healthier lives.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults (≥18 years old)
• • Diagnosis of borderline personality disorder according to the SCID-II (≥5 out of 9 criteria)
• • Provision of written informed consent
• • Affiliated with or beneficiary of the French national health insurance system
• • Exclusion criteria
• • Age under 18 years
• • Presence of a comorbid psychotic disorder, intellectual disability, severe antisocial traits, major substance use disorder incompatible with intensive therapy without abstinence, anorexia nervosa with somatic risk, or bipolar disorder in acute manic phase
• • Individuals under legal protection (e.g., guardianship or legal safeguard)
• • Individuals unable to cooperate or complete self- or clinician-administered questionnaires
• • Individuals not affiliated with or not beneficiaries of the French national health insurance system