Clinical Association Between Celiac Disease and Intussusception in Children

Launched by MERNA HAMDY KAMAL MOHAMMED · Mar 31, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at the relationship between celiac disease and a condition called intussusception in children. Celiac disease is an autoimmune disorder where eating gluten (a protein found in wheat, barley, and rye) damages the small intestine. Intussusception occurs when part of the intestine folds into another part, which can cause blockages. The researchers want to see if children with celiac disease are more likely to develop intussusception compared to those without the disease.

To participate in the trial, children must be between 6 months and 18 years old, have a confirmed diagnosis of celiac disease, and have been diagnosed with intussusception through imaging tests. Parents or guardians will need to give their consent for their child to join. However, children with certain gastrointestinal problems, those who have had abdominal surgery, or those on specific medications that weaken the immune system cannot participate. The trial is not yet recruiting participants, but it aims to gather important information about how these two conditions may be connected in young patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children aged 6 months to 18 years Diagnosed with celiac disease based on serology and biopsy Diagnosed with intussusception confirmed by imaging Parent or legal guardian provides informed consent
• Exclusion Criteria:
• • Children with known gastrointestinal abnormalities other than celiac disease History of abdominal surgery Incomplete or unavailable medical records Patients on immunosuppressive therapy