Pain Relief Comparison: Pericapsular Nerve Group Versus Quadratus Lumborum Block for Positioning in Femur Fracture Surgery
Launched by AIN SHAMS UNIVERSITY · Apr 4, 2025
Trial Information
Current as of July 21, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is comparing two different methods of providing pain relief for patients undergoing surgery for hip fractures. The study will look at the effectiveness of two types of nerve blocks – the Pericapsular Nerve Group Block (PENG) and the Quadratus Lumborum Block (QLB) – in helping manage pain during the positioning of patients for spinal anesthesia. A total of 42 adults will participate, and they will be divided into two groups to receive one of the two nerve blocks. The researchers will assess pain levels before and after the blocks are given, as well as how soon patients need additional pain relief after surgery.
To be eligible for this study, participants need to be adults over the age of 21 who are scheduled for surgery to fix a hip fracture. They should be in good health overall but can have some minor medical conditions. However, individuals who have certain serious health issues, are on long-term opioid pain medications, or have specific infections or allergies will not be able to participate. Throughout the trial, patients will be monitored for their pain levels and any side effects, ensuring their safety and comfort during the process.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adult patients aging \> 21 years of both sexes.
- • Patients scheduled for fixation of proximal femur fracture under spinal anesthesia.
- • ASA Physical Status Class I, II or ш.
- Exclusion Criteria:
- • Patient refusal to participate.
- • Patients receiving opioids for chronic analgesic therapy.
- • in ability to comprehend the visual analog scale.
- • Coagulopathy ( INR \> 1.4, platelets \< 80000/mm3, or bleeding disorder).
- • Infection at the injection site.
- • Allergy to local anesthetics.
- • Polytroma patients ( e.g., concurrent major thoracic/ abdominal injuries)
- • Severe cardiopulmonary disease (e.g., low fixed cardiac output, NYHA class 3/4).
- • Neurological disease (e.g., peripheral neuropathy, multiple sclerosis).
About Ain Shams University
Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, Abbasia, Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported