Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria
Launched by ODENSE UNIVERSITY HOSPITAL · Apr 2, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how common colorectal cancer and precancerous tumors are in patients over 18 years old who have a specific type of blood infection caused by certain bacteria from the gut. The researchers want to find out how often these cancers are found in the large intestine and rectum of people who are hospitalized for this infection. If you qualify for the study, you'll be invited to have a special examination called a colon capsule endoscopy about 4 to 8 weeks after you leave the hospital. This test uses a small camera that you swallow, allowing doctors to see inside your colon without needing traditional surgery.
To be eligible for this study, you need to be at least 18 years old and have had a blood test that shows you have one of the specific types of bacteria mentioned. However, there are some reasons you might not be able to participate, such as having certain gastrointestinal conditions or previous surgeries. It’s important to understand that this study is not yet recruiting participants, so it may take some time before you can join if you are interested.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Older than 18 years
- • Blood culture with growth of one or more of the following bacterial genera Bacteroides, Clostridium, Filifactor, Fusobacterium, Gemella, Granulicatella, Parvimonas, Peptostreptococcus, Prevotella, Solobacterium, Peptoniphilus, Ruminococcus, Finegoldia and Streptococcus.
- • Able to provide oral and written informed consent
- • Able to read and speak Danish
- Exclusion Criteria:
- • Prior colorectal cancer diagnosis
- • History of stenosis of the gastrointestinal tract
- • Previous treatment of inflammatory bowel disease
- • Previous major surgery of the gastrointesinal tract (e.g. gastric bypass)
- • Colostomy
- • Pacemaker/ICD
- • Pregnancy or breastfeeding
- • Allergies to the bowel preparation regimen
- • Severe kidney disease
- • Focus of infection in skin and soft tissue or outside the truncus (e.g. decubitus, diabetic foot ulcer)
- • Tumor in the colon or rectum at diagnostic imaging
- • Discharge before result of blood culture
- • Transfer to other hospital outside the region
About Odense University Hospital
Odense University Hospital is a leading academic medical center located in Denmark, dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital is committed to enhancing patient outcomes and fostering collaboration among multidisciplinary teams. With a focus on translating scientific discoveries into practical applications, Odense University Hospital leverages its state-of-the-art facilities and expertise to conduct rigorous trials across various medical fields, ensuring adherence to the highest ethical and regulatory standards. Through these efforts, the hospital aims to contribute significantly to the global body of medical knowledge and improve the quality of care for patients both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Odense, , Denmark
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported